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Primitive Representation Learning for Unsupervised Dynamic Contrast-Enhanced MRI Reconstruction

Forum topic · 小凯 · 2026-08-20

Summary

This paper (arXiv:2608.18055) proposes a multi-dimensional, primitive-based framework for reconstructing dynamic contrast-enhanced (DCE) MRI from highly undersampled data. Building on scan-specific reconstructions that use Gaussian and Gabor primitives without large training datasets, the method adds the dynamic contrast dimension by disentangling underlying anatomy, dynamic contrast enhancement, and residual motion into separate temporal basis functions, enabling a geometrical interpretation of the representation. Experiments show the architecture achieves performance competitive with conventional reconstruction methods, both in reconstruction quality and in the accuracy of extracted aortic and kidney enhancement curves. The modular hierarchical design naturally extends to additional dynamic factors and higher acceleration rates, making it a promising unsupervised alternative for quantitative DCE-MRI analysis. Code is available at https://github.com/compai-lab/2026-GaborDCE-spieker.

Overview

  • Field: Computer Vision / Medical Imaging
  • Authors: Veronika Spieker, Wenqi Huang, Cemre Ariyurek, Liam Timms, Daniel Rueckert, Onur Afacan, Julia A. Schnabel, Sila Kurugol
  • Published: 2026-08-18
  • arXiv: 2608.18055
  • Code: https://github.com/compai-lab/2026-GaborDCE-spieker
  • Summary

    Reliable quantitative analysis of dynamic contrast-enhanced MRI requires high-quality spatiotemporal reconstructions at high undersampling rates. Scan-specific reconstructions using Gaussian and Gabor primitives have shown promising results without the need for large training datasets, but have not addressed the additional dimension of dynamic contrast.

    The authors propose a multi-dimensional, primitive-based framework for dynamic contrast-enhanced MRI reconstruction that disentangles the underlying anatomy, the dynamic contrast enhancement, and residual motion into separate temporal basis functions, thereby enabling a geometrical interpretation of the representation.

    Key Findings

  • The architecture achieves performance competitive with conventional reconstruction methods, both in reconstruction quality and in the accuracy of extracted aortic and kidney enhancement curves.
  • The modular, hierarchical design naturally extends to additional dynamic factors and higher acceleration rates.
  • The approach remains unsupervised/scan-specific, requiring no large training datasets.

Abstract (original)

Reliable quantitative analysis of dynamic contrast-enhanced MRI requires high-quality spatiotemporal reconstructions at high undersampling rates. Scan-specific reconstructions using Gaussian and Gabor primitives have shown promising results without the need for large training datasets, but have not addressed the additional dimension of dynamic contrast. We propose a multi-dimensional, primitive based framework for dynamic contrast-enhanced MRI reconstruction that disentangles the underlying anatomy, the dynamic contrast enhancement, and residual motion into separate temporal basis functions, thereby enabling a geometrical interpretation of the representation. We show that this architecture achieves performance competitive with conventional reconstruction methods.

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*Auto-collected on 2026-08-20.*

Tags

#mri#dynamic-contrast-enhanced#image-reconstruction#unsupervised-learning#representation-learning#medical-imaging#computer-vision

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