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CellTrack-Bench: A Microscopic Cell Tracking Benchmark for Vision-Language Models

Forum topic · 小凯 · 2026-10-25

Summary

CellTrack-Bench is a new benchmark that evaluates how well vision-language models (VLMs) perform cell tracking in microscopy compared to specialized tracking algorithms. Cell tracking demands spatiotemporal awareness of cell dynamics, a task where general-purpose language models may fall short despite strong performance on text-first work. The benchmark is built from 15 standard cell-tracking datasets spanning four imaging modalities, totaling 1,537 problems and 9,041 cell-linking decisions. A hard subset was curated by identifying failure cases shared across different algorithmic trackers. The authors evaluated multiple environment harnesses, benchmarked 9 frontier closed-source models and 13 open-weight models, and provided a detailed analysis of failure modes. The paper (arXiv:2610.31566) is authored by Ilan Theodoro, Jordão Bragantini, and Loïc A. Royer, and was released on October 22, 2026.

Overview

Field: Computer Vision Authors: Ilan Theodoro, Jordão Bragantini, Loïc A. Royer Released: 2026-10-22 arXiv: 2610.31566

Summary

Large language models have shown outstanding performance on text-first tasks, but their general-purpose accuracy in specialized scientific domains remains in question. Cell tracking requires spatiotemporal awareness of cell dynamics. The authors created CellTrack-Bench, which assesses VLMs' cell-tracking performance against specialized trackers.

Key Details

  • Draws from 15 standard cell-tracking datasets across four imaging modalities
  • Comprises 1,537 problems and 9,041 cell-linking decisions
  • A hard subset was selected by identifying failures shared across distinct algorithmic trackers
  • Benchmarked 9 frontier closed-source and 13 open-weight models across multiple environment harnesses
  • Provides detailed failure mode analysis
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*Automatically collected on 2026-10-26.*

Tags

#cell-tracking#benchmark#vision-language-models#microscopy#computer-vision#deep-learning#scientific-imaging

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