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GazeRIB: Multi-Reader Gaze-Guided Chest X-ray Classification Outperforms Single-Reader Supervision

Forum topic · 小凯 · 2026-11-03

Summary

GazeRIB (Gaze-guided Radiologist-Informed Blackout) is a method that masks unviewed regions of medical images during model training while using unmasked images at inference, leveraging radiologists' visual attention as supervision. Researchers had eight experts repeatedly read the same 80 chest X-rays and compared individual readers against three-, five-, and eight-reader panels across seven architectures and 10 random seeds, evaluating 910 models on a separate 2,897-image cohort for four-class severity prediction. Every panel improved macro F1 by 5.33-7.47 percentage points over the no-gaze baseline (Bonferroni-adjusted p < 0.007), while no individual reader reached significance. Three readers captured 73-80% of the eight-reader panel's gain in macro F1, ROC-AUC, and AU-PRC. External validation on SIIM-FISABIO-RSNA showed ROC-AUC gains of +1.93 to +4.24 points for all panels without retraining (p <= 0.004), while on MIMIC-Eye panels showed no significant difference and single readers declined on average (-1.40 pp, p = 0.008). The study demonstrates that reader panel composition materially affects gaze-guided learning performance, with transfer behavior depending on the target cohort.

Paper Overview

Field: Computer Vision Authors: Nattakorn Kittisut, Roy M. Gabriel, Marly van Assen, Mohammadreza Zandehshahvar, Carlo N. De Cecco, Elizabeth A. Krupinski, Ali Adibi Published: 2026-10-30 arXiv: 2610.42152

Summary

Radiologists' visual attention can supervise medical image learning, but how reader panel composition affects its value remains untested. The authors evaluated GazeRIB (Gaze-guided Radiologist-Informed Blackout), which masks unviewed regions during training and uses unmasked images at inference.

Eight experts repeatedly read the same 80 chest X-rays (CXRs). The study compared individual readers with three-, five- and eight-reader panels across seven architectures and 10 random seeds, evaluating 910 models on a separate 2,897-CXR cohort for four-class severity prediction.

Key Findings

  • Every reader panel improved macro F1 over the no-gaze baseline by 5.33-7.47 percentage points (pp; Bonferroni-adjusted p < 0.007); no individual reader reached significance on this endpoint.
  • Three readers captured 73-80% of the eight-reader panel's gain in macro F1, ROC-AUC, and AU-PRC.
  • In external validation without retraining, all four panels improved ROC-AUC on the SIIM-FISABIO-RSNA dataset by +1.93 to +4.24 pp (p <= 0.004).
  • On MIMIC-Eye, all panels showed no significant difference from baseline, while individual readers declined on average (-1.40 pp, p = 0.008).

Conclusion

Reader panel composition affects the value of gaze-guided supervision: even small panels of three readers deliver most of the benefit of larger panels, though transfer performance depends on the target cohort.

Original Abstract

> Radiologists' visual attention can supervise medical image learning, but how reader panel composition affects its value remains untested. We evaluated GazeRIB (Gaze-guided Radiologist-Informed Blackout), which masks unviewed regions during training and uses unmasked images at inference. Eight experts repeatedly read the same 80 chest X-rays (CXRs). We compared individual readers with three-, five- and eight-reader panels across seven architectures and 10 seeds, evaluating 910 models on a separate 2,897-CXR cohort for four-class severity prediction. Every panel improved macro F1 over the no-gaze baseline by 5.33-7.47 percentage points (pp; Bonferroni-adjusted p < 0.007); no individual reader reached significance on this endpoint. Three readers captured 73-80% of the eight-reader gain in mac...

--- *Auto-collected on 2026-11-03*

Tags

#gaze-guided-learning#medical-imaging#chest-x-ray#radiology#deep-learning#computer-vision#arxiv#gazerib

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